Claude Fable 5, Anthropic’s new Mythos-class model for general use, is here. Sort of.

Anthropic says the underlying Mythos model is now seriously useful for research biology, including drug design, molecular-biology hypotheses and autonomous genomics work. But the public version, Fable, routes most biology and chemistry requests away from that strongest model for safety reasons.

I have opinions on this and felt it best belonged in it’s own post. To give you a sense of where I stand I’ll give you the headline: Scientists are the new refugees in Dario Amodei's world.

In this issue we also have Tahoe’s shortcut around virtual cells, NewLimit’s AI machinery for aging reprogramming, and AstraZeneca’s attempt to predict Phase 3 success.

Let’s dive in.